Carbimazole

Carbimazole--resistant thyrotoxicosis.

Jaundice due to carbimazole.

On three occasions, a 63 year old housewife with hyperthyroidism developed a reaction which included fever, pruritus, malaise, and, on one occasion, jaundice one to 17 days after taking carbimazole. Challenge with carbimazole was followed within 12 hours by abdominal pain, pruritus, and increased serum transaminase levels. Light microscopy of a liver biopsy showed increase of portal zone cellul...

Carbimazole (Neo-Mercazole) in Thyrotoxicosis

stressed the freedom from toxicity and potency of carbimazole as an anti-thyroid drug. Though potent, thiourea derivatives had proved to have a significant toxic risk. For this reason, most recent workers have concentrated on a comparison of carbimazole with thiourea drugs in regard to studies of toxicity. McGavack, et al. (1956), in describing their experiences in forty-one cases with special ...

Carbimazole Embryopathy and Choanal Atresia

Congenital choanal atresia (CCA), especially the bilateral form, is a rare neonatal emergency. Its incidence is usually quoted as 1 in 5000 8000 live-births. [1] However, a recent epidemiological study involving more than 2.2 million deliveries suggests that CCA is extremely rare with a calculated incidence of 3 to 9 per 100,000 livebirths. [2] Athena is fascinated by CCA not only due to its ra...

Carbimazole Induced Pleural Effusion: A Case Report

Objective. To describe a patient with unilateral exudative pleural effusion that developed after commencement of carbimazole. Methods. We describe the presentation and clinical journey of an elderly woman who presented to the chest physicians initially with pleural effusion but was followed up by the endocrinology team. Result. The patient was a 77-year-old Caucasian woman who presented with sy...